MSUM Physics and Astronomy Seminar Series this Friday
Friday, Apr. 15 | 3 – 3:50 pm | Hagen 325
Ryan Bosca, research associate, (Department of Medical Physics, University of Wisconsin, Madison) will present on “Functional Magnetic Resonance Imaging: A Pathway to Objectively Quantifying Biological Processes.”
Routine clinical magnetic resonance imaging (MRI) exploits intrinsic tissue properties (e.g., diffusion, perfusion, and the chemical environment) to generate tissue contrast within images that are evaluated subjectively by a trained reader. Functional MRI utilizes these same tissue properties, but, through the application of an appropriate mathematical model and/or image processing algorithm, quantitative biophysical tissue characteristics can be derived. The successful implementation and application of such techniques can yield quantitative imaging biomarkers (QIB) – objective measures of normal and pathogenic biological processes1. Researchers and clinicians are increasingly focusing on the development and implementation of these techniques, as QIBs can potentially contribute to the advancement of personalized medicine. This presentation will outline some of the techniques and models from which QIBs are derived and highlight a number of potential applications.
1Sullivan et al., Radiology 277(3):813-825, 2015 (www.rsna.org/qiba)